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This formula is indicated for lack of both Qi and blood. The formula is the combination of two smaller formulas, The Four Gentlemen (Si Jun Zi Tang), to tonify Qi, and The Four Substances (Si Wu Tang) to tonify blood. Codonopsis (dang shen) tonifies the Qi while rehmannia (shu di huang) nourishes the blood. White atractylodes (bai zhu) and poria (fu ling) strengthen the spleen and remove dampness thereby assisting codonopsis. White peony (bai shao) and tang kuei (dang gui) nourish the blood and assist rehmannia in this capacity. An additional herb, spatholobus (ji xue teng) has been added to enhance the formula's ability to both move and tonify the blood. Along with ligusticum (chuan xiong), the formula now takes on the increased ability to create new blood, making it valuable to athletic performers who tend to have exhausted blood. Licorice (zhi gan cao) tonifies the Qi and harmonizes the middle burner. Ginger (gan jiang) and red date (da zao) regulate the absorbing function of the spleen and stomach.
Codonopsis root (dang shen), White Atractylodes rhizome (bai zhu), Poria sclerotium (fu ling), Rehmannia (cooked) root (shu di huang), White Peony root (bai shao), Tang Kuei root (dang gui), Ligusticum root (chuan xiong), Spatholobus stem (ji xue teng), Baked Licorice root (zhi gan cao), Ginger rhizome (gan jiang), Red Date fruit (da zao)